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What is Profhilo?

As we age, the loss of collagen and elastin from our skin will inevitably cause our skin to sag, lose elasticity, and exhibit other signs of aging. While this is a natural part of the ageing process, we can slow it down or even turn back the clock with available aesthetic treatments.

Profhilo can do wonders in turning back the hands of the clock to help you regain youth.



Profhilo is an injectable skin remodelling treatment that originated from Italy, which contains one of the highest concentrations of Hyaluronic Acid (HA) and it is designed for people whose skin lacks firmness and elasticity.

Now Profhilo is readily available in Singapore and is commonly used as a skin rejuvenation treatment.

Scientifically, Profhilo is a Hybrid Complex made of H-HA and L-HA, 2 different molecular weights that have is very beneficial to the skin. The high molecular weight of the HA is able to protect the skin’s integrity and ability to retain moisture while the low molecular weight HA hydrates the skin with its hydrophilic properties. 

Formulated with patented NAHYCO Hybrid Technology, the stabilised hybrid HA cooperative complex is produced without the addition of any chemical cross-linking compounds (i.e. BDDE-free).


The slow release of HA by Profhilo stimulates the production of collagen and elastin, in turn improving skin tone, hydration and the appearance of fine lines. The result is improved skin quality lasting for up to 6 – 9 months.


Benefits of Hybrid HA cooperative complexes:

  • More resistant to degradation by hyaluronidase enzymes, and last longer
  • BDDE-free and more biocompatible
  • Less viscose and more spreadable
  • Less risk of inflammation and granulomas
  • Chemical-free


How does it work?

HA is hydrophilic, drawing and holding water from your body, transforming those with tired, dry, dull-looking skin, transforming it into firm and luminous skin. This effect takes place over the course of 2 -4 weeks of treatment.

Over the next few weeks, collagen and elastin production is stimulated, producing a secondary effect of skin tightening. This is useful because levels of collagen, elastin and Hyaluronic Acid in the skin rapidly drop from the age of 30, resulting in signs of ageing such as fine lines, wrinkles and lacklustre skin.


Profhilo acts to reverse some of these changes. The maximum effect of Profhilo is usually seen 2 months after the second treatment.

Profhilo is injected just below the skin’s surface over 2 sessions 4 weeks apart. After injection it disperses quickly beneath the skin to improve hydration, without any need for massage or risk of leaving lumps or nodules. Profhilo is absorbed within a 2cm radius of its injection site, so to treat the face only 10 injection points are needed in total.


A single course of Profhilo involves 2 – 3  injectable treatments 4 weeks apart, after which you can expect to see intense hydration. It makes the skin glow, improvement in fine and you’ll notice smoother, tighter skin.


What are the benefits of PROFHILO?


  • Bio-stimulates elastin, 4 types of collagen and hydration in the 3 main layers of the skin
  • Provides firming, tightening and lifting effect to the skin
  • Improves overall skin quality and hydration
  • Fast and effective treatment with minimal pain and downtime
  • Provides tissue repair process, ideal for acne scarring
  • Intense hydration with anti-inflammatory properties, complementary
  • Chemical free



Profhilo is most suitable for:

  • mild to moderate skin laxity
  • poor skin quality
  • fine lines
  • dull and dry skin
  • those keen for natural-looking enhancement, without looking too artificial


Why choose PROFHILO?

Profhilo uses a unique injection method –  BAP (bio-aesthetic points) technique, injection sites are carefully selected across the face for optimal product diffusion and to minimize risk to nerves and blood vessels. Profhilo is injected only on five points of each side of the face (with a total of 10).


The BAP technique also delivers a natural and lasting refreshed appearance. This helps achieve maximum results with less risk/discomfort and fewer sessions. 



Profhilo can be used for skin rejuvenation for the following areas:


  • Cheeks & lower face
  • Neck & Décolletage
  • Hands
  • Depressed acne scars



Is there downtime for Profhilo?

There is no to minimal downtime. You may experience a little swelling at the few injection points right after the treatment, but these will subside usually within 24 hours as it spreads easily into the intracellular space.


Small bruises although uncommon may occur over the injection site and can be easily concealed with concealer/ make up.



Can it be combined with other treatments?


Yes, other medical aesthetic treatments can be combined with Profhilo. It is best to consult your doctor to discuss which treatment should be performed first to optimise your treatment results.


What is the difference between Profhilo and other dermal fillers/skin boosters

Many may mistake Profhilo as other skin boosters or fillers. However, it is not a lifting filler and does not replace other types of filler. And although all contain hyaluronic acid, Profhilo is a bio remodeling skin injectable that treats skin laxity and boosts collagen and elastin levels.


Fillers, for the most part, fill up lost volume and offers instant volume replacement and contouring. Skin boosters, on the other hand, improves skin elasticity and restores hydration at the treatment area. Profhilo, meanwhile, lifts and hydrates the skin, as well as improves the skin’s overall integrity.


Authenticity check

It is important to look out for our QR code to ensure that your doctor is using an authentic Profhilo. In Singapore, the Neoasia   sticker+*/+96+*———————-ial number are found on Profhilo® boxes.


You are encouraged to scan the QR code with your mobile phone to authenticate the Profhilo® product. A verified product ensures that the source of Profhilo® is authentic and delivered via pharmaceutical cold chain logistic, ensuring product integrity, safety and efficacy.



Price of Profhilo in Singapore

Prices/cost of Profhilo range from $1000 for 2cc (excl gst), per treatment session.

Depending on your skin condition, more than 1 Profhilo treatment session might be needed to achieve desired results.




At M-Aesthetic Clinic, we offer Profhilo, skin boosters and other skin rejuvenation treatments. Before starting any treatment, a consultation is necessary and will be done by Dr Ho as he will need to assess your skin condition, lifestyle preferences and customise the treatment for you.


Get in touch with us to find out more on how Profhilo can help bring back your skin’s youth.


Contact Us




M-Aesthetic Clinic

Novena Medical Center,
#11-07/08, 10 Sinaran Drive
Singapore 307506

Weekdays: 11am – 8pm
Saturdays: 10am – 3pm
Sundays: Closed
Call | Whatsapp: +65 8129 9120
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