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Weight Loss


Saxenda: A Comprehensive Guide to Effective Weight Loss

Losing weight can be a challenging journey, especially for individuals struggling with obesity. Obesity not only affects one’s physical appearance but also poses significant health risks. In such cases, medical intervention can be crucial to achieving and maintaining a healthy weight.

Saxenda, a prescription weight loss medication, has emerged as a valuable tool in the battle against obesity. In this comprehensive guide, we will delve into what Saxenda is, its mechanism of action, the impact of obesity on health, common side effects, dosing, and the importance of working with a healthcare professional.


What is Saxenda?

Saxenda is a prescription weight loss medication approved by the U.S. Food and Drug Administration (FDA) and HSA Singapore to aid in weight loss for individuals who are struggling with obesity.

It belongs to a class of medications known as GLP-1 receptor agonists (GLP-1 RAs). Saxenda is essentially a synthetic form of the hormone GLP-1, which is naturally produced in the gut. GLP-1 plays a vital role in regulating blood sugar levels, appetite, and body weight.


What is GLP-1 RAs?

GLP-1 RAs stands for “Glucagon-Like Peptide-1 Receptor Agonists.” These are a class of medications used primarily to manage blood sugar levels in individuals with type 2 diabetes. GLP-1 RAs work by mimicking the actions of a hormone called glucagon-like peptide-1 (GLP-1), which is naturally produced in the intestines.

Effects of GLP-1:

–  Helps regulate blood sugar levels by stimulating insulin release,

–  Slows down stomach emptying,

–  Reduces appetite and,

–  Inhibits the release of glucagon (a hormone that raises blood sugar).

By using GLP-1 RAs, individuals with type 2 diabetes can improve their blood sugar control, leading to better overall health. Some medications in this class include Semaglutide (sold under brand names like Ozempic, Rybelsus, and Wegovy) and Liraglutide (marketed as Saxenda).

In addition to diabetes management, some GLP-1 RAs (Saxenda & WeGovy) have also been approved for weight loss purposes due to their ability to reduce appetite and promote a sense of fullness, making them valuable tools in addressing both diabetes and obesity.

How Saxenda Works

Saxenda’s mechanism of action centers around its role as a GLP-1 receptor agonist. GLP-1 is a naturally occurring hormone that regulates blood sugar levels and helps control appetite.

Saxenda mimics the effects of GLP-1 in the body, leading to several weight loss-promoting effects:

  • Increases the feeling of fullness (satiety): Saxenda sends signals to the brain that you are satisfied, reducing the urge to overeat.

  • Delays gastric emptying: It slows down the emptying of food from the stomach, which helps control post-meal blood sugar spikes.

  • Reduces appetite: Saxenda acts on the brain’s hunger center, decreasing feelings of hunger and cravings.


How is Saxenda administered?

Saxenda is administered as a once-daily injection.


Benefits Beyond Weight Loss

Cardiovascular Benefits

Improved Blood Pressure

Lowered Blood Glucose
Levels & Risk of Diabetes

69% of Pre-diabetic Patients
Returned to Normal Glycaemic Status
After 1 Year


Common Side Effects of Saxenda

Like any medication, Saxenda may have side effects.

Common side effects include:

–  Nausea,

–  Vomiting,

–  Diarrhoea,

–  Constipation,

–  Bloating,

–  Abdominal pain.

These side effects are typically mild to moderate in intensity and tend to diminish over time. It is essential to discuss any side effects with your healthcare provider.

If you do experience nausea, here are some things that may help:

• Eat smaller meals
• Stop eating when you are full
• Avoid the food and smells that make you feel worse

Keep in mind that in most cases, nausea goes away after a few days


Dosing Schedule

Saxenda is administered as a subcutaneous injection (under the skin) once daily. It is crucial to follow the prescribed dosing schedule provided by your healthcare provider. Typically, Saxenda treatment begins with a lower dose, which is gradually increased to the maintenance dose over several weeks. Adhering to the recommended dosing schedule is essential for the medication’s effectiveness.


Dosing Pen

Saxenda is available in a pre-filled, multi-dose pen that simplifies the injection process. The pen allows for easy and convenient self-administration, making it a user-friendly option for individuals on a weight loss journey. Your healthcare provider will provide detailed instructions on how to use the Saxenda dosing pen.

Working with a Health Care Professional

Embarking on a weight loss journey with Saxenda is not a solo endeavour. Working closely with a healthcare professional is crucial to ensure safe and effective treatment.

At M-Aesthetic Clinic, we provide the following: 

  • Personalised Treatment: We tailor Saxenda treatment to your specific needs and goals, ensuring a personalised approach to weight loss.

  • Monitoring and Adjustments: Regular check-ins allow for the monitoring of progress and any potential side effects. Adjustments to the treatment plan can be made if necessary.

  • Lifestyle Guidance: We offer guidance on adopting a healthier lifestyle, including dietary changes and increased physical activity.

  • Addressing Health Concerns: If you have underlying health conditions, we can assess how Saxenda may impact them and adjust the treatment plan accordingly.

In conclusion, Saxenda, a GLP-1 receptor agonist, plays a crucial role in the battle against obesity by regulating blood sugar levels and curbing appetite. However, it’s vital to recognize that tackling obesity’s complexities and associated health risks necessitate a collaborative effort with a healthcare professional. Together, a personalised treatment plan can be crafted, offering individuals a promising path to achieving and sustaining a healthy weight.

Saxenda, as part of this comprehensive strategy, enhances the prospects of a healthier future, improving one’s quality of life and mitigating the health risks linked to obesity-related conditions.

Contact Us




M-Aesthetic Clinic

Novena Medical Center,
#11-07/08, 10 Sinaran Drive
Singapore 307506

Weekdays: 11am – 8pm
Saturdays: 10am – 3pm
Sundays: Closed
Call | Whatsapp: +65 8129 9120
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