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Profhilo treatment in Singapore is an injectable skin remodelling treatment originated from Italy. Containing one of the highest concentrations of Hyaluronic Acid (HA), it is designed for people whose skin lacks volume and elasticity.

In scientific terms, Profhilo is a Hybrid Complex made of H-HA and L-HA, 2 different molecular weights that has is very beneficial to the skin. The high molecular weight of the HA is able to protect the skin’s integrity and ability to retain moisture while the low molecular weight HA hydrates the skin with its hydrophilic properties.

The patented NAHYCO Hybrid Technology formulation allows stabilised hybrid HA cooperative complex to be produced without the addition of any chemical cross-linking compounds (i.e. BDDE-free).

Benefits of Hybrid HA cooperative complexes:

  • More resistant to degradation by hyaluronidase enzymes, and last longer
  • BDDE-free and more biocompatible
  • Less viscose and more spreadable
  • Less risk of inflammation and granulomas

It stimulates the production of collagen and elastin, in turn improving skin tone, hydration and the appearance of fine lines. The result is improved skin quality lasting for up to 6 months.

How does it work?

HA is hydrophilic, draws and contains water, transforming dull-looking skin into firm and luminous skin. This effect starts to take place within 3-5 days of treatment.

Over the next few weeks, collagen and elastin production is stimulated, producing a secondary effect of skin tightening. This is useful because levels of collagen, elastin and Hyaluronic Acid in the skin rapidly drop from the age of 30, resulting in signs of ageing such as fine lines, wrinkles and lacklustre skin. Profhilo acts to reverse some of these changes. 

It is injected just below the skin’s surface and it spreads quickly beneath the skin without any need for massage or risk of leaving long term lumps or nodules.  2 -3 sessions with a month between sessions are recommended for optimal results.


What are the benefits of PROFHILO?

  • Bio-stimulates elastin, 4 types of collagen and hydration in the 3 main layers of the skin
  • Provides firming, tightening and lifting effect to the skin
  • Improves overall skin quality and hydration
  • Fast and effective treatment with minimal pain and downtime
  • Provides tissue repair process, ideal for acne scarring
  • Intense hydration with anti-inflammatory properties, complementary

Profhilo is most suitable for:

  • middle-age individuals
  • mild to moderate skin laxity
  • poor skin quality
  • fine lines
  • dull and dry skin
  • those keen for natural-looking enhancement, without looking too artificial


Profhilo can be used for skin rejuvenation for the following areas:

  • Cheeks & lower face
  • Neck & Décolletage
  • Hands
  • Depressed acne scars

Why Choose M-Aesthetic Clinic?

10+ Years of Experience

Trusted by 10,000+ Patients

Safe & Proven Results

Frequently Asked Questions ABOUT PROFHILO

Is there downtime for Profhilo?

The downtime is minimal. You may experience a little swelling at the few injection points right after the appointment, but these will subside within 24 – 48 hours given that it spreads easily into the intracellular space.


Small bruises over the injection site can be easily concealed as large blood vessels are avoided with the specially designed BAP injection technique with fewer injection points (5 injection points per side of face).

Can it be combined with other treatments?

Yes, other medical aesthetic treatments can be combined with Profhilo. It is best to consult to discuss which treatment should be performed first to optimise your treatment results.


How many syringes will I need?

It will depend on the size of your face and the amount of hydration needed. Averagely, one would need about 2cc for the face and another 2cc for the neck.

Are there any side effects?

There are no side effects but some may experience micro bruises on the treated areas.

Contact Us




M-Aesthetic Clinic

Novena Medical Center,
#11-07/08, 10 Sinaran Drive
Singapore 307506

Weekdays: 11am – 8pm
Saturdays: 10am – 3pm
Sundays: Closed
Call | Whatsapp: +65 8129 9120
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